Psoriasis

Psoriasis is a complex chronic inflammatory skin disease with aberrant immunopathogenetic mechanisms. The pathogenesis includes hyperkeratotic plaques, usually localized on the scalp, elbows, knees and buttocks, and are characterized by cutaneous inflammatory infiltrates, epidermal hyperplasia and impaired keratinocyte differentiation, and hypervascularity in the upper skin (epidermis / dermis). Clinically, it manifests as redness and peeling.