{"id":7410,"date":"2021-05-19T09:52:46","date_gmt":"2021-05-19T07:52:46","guid":{"rendered":"https:\/\/www.hempethica.com\/?p=7410"},"modified":"2024-01-19T11:05:56","modified_gmt":"2024-01-19T10:05:56","slug":"terpeni-in-njihov-entourage-efekt-s-kanabinoidi","status":"publish","type":"post","link":"https:\/\/www.hempethica.com\/si\/terpeni-in-njihov-entourage-efekt-s-kanabinoidi\/","title":{"rendered":"Terpeni in njihov \u00bbEntourage\u00ab efekt s kanabinoidi"},"content":{"rendered":"\t\t
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Terpeni in njihov “Entourage” efekt s kanabinoidi<\/h2>\n

Terpeni so ene glavnih spojin v vsaki rastlini. So gradniki eteri\u010dnih olj. Njihova vsestranska uporabnost se za\u010dne \u017ee v rastlinah, kjer v dolo\u010denih primerih delujejo kot njihova naravna za\u0161\u010dita pred \u0161kodljivci in zajedavci. Gre za hlapne, aromati\u010dne molekule, mo\u010dnega vonja in okusa. So spojine, ki so v strokovnem svetu \u017ee zelo dobro raziskani. Razli\u010dni strokovnjaki, znanstveniki in raziskovalci iz celotnega sveta so poudarili farmakolo\u0161ki pomen terpenov in eteri\u010dnih olj, ki so osnova aromaterapije, v svetu zelo priljubljenega alternativnega celostnega na\u010dina zdravljenja.<\/p>\n\n

Prepri\u010dljiv vonj in di\u0161ava konoplje sta odvisna od prevladujo\u010dih posameznih terpenov. Razli\u010dne sorte konoplje imajo razli\u010den kanabinoidni profil, prav tako to velja za terpenski profil.<\/p>\n\n

V konoplji je bilo do tega trenutka najdenih, opisanih in raziskanih \u017ee pribli\u017eno 200 razli\u010dnih terpenov. Med njimi so monoterpeni, diterpeni in seskviterpeni, za vse pa je zna\u010dilno \u0161tevilo ponavljajo\u010dih se enot molekule izoprena, ki je strukturni znak vseh terpenoidnih spojin.<\/p>\n\n

Raziskave so pokazale, da so terpeni zdravi za ljudi, \u017eivali in tudi rastline. Eden vidnej\u0161ih strokovnjakov na podro\u010dju raziskovanja terpenov, dr. Ethan Russo<\/a> je objavil \u017ee vrsto strokovnih \u010dlankov na temo terpenov, kanabinoidov in njihovega pozitivnega delovanja na na\u0161e telo in je eden vidnej\u0161ih strokovnjakov na tem podro\u010dju. Eno najobse\u017enej\u0161ih raziskav na podro\u010dju terpenov, uporabnosti za zdravje in sinergijskih efektov je opisal v reviji British Journal of Pharmacology<\/em>, kjer opisuje delovanje terpenov, ki jih najdemo v konoplji.<\/p>\n\n

V rastlinah se terpeni in kanabinoidi sintetizirajo v trihomih s pomo\u010djo encimov. Vsebnost oz. koncentracija posameznih molekul je odvisna od ve\u010d faktorjev, predvsem pa je to funkcija genetike. Ob upo\u0161tevanju dejstva, da je konoplja ena izmed najbolj raziskanih rastlin na svetu, lahko z gotovostjo trdimo, da sestavine konoplje blagodejno delujejo na na\u0161e telo.<\/p>\n\n

\"\"<\/figure>\n\n

V konoplji prevladujejo predvsem monoterpeni, limonen, pinen in mircen ter seskviterpen kariofilen. Njihova vsebnost v trihomih zna\u0161a cca 10%, kar predstavlja do cca 1% celotnega cveta.<\/p>\n\n

Farmakolo\u0161ko gledano so terpeni vsestranski. Medsebojno interagirajo s celi\u010dnimi membranami, nevronskimi in mi\u0161i\u010dnimi ionskimi kanali, nevrotransmiterskimi receptorji, receptorji, povezanimi z G-proteini (odorantnimi), sistemi za sekundarno selitev in encimi. Vsi terpeni so \u00bbGRAS\u00ab oz. \u00bbGenerally Recognized as Safe\u00ab kot to navaja ameri\u0161ka FDA, Food and Drug Administration (agencija za hrano in zdravila), kar v prevodu pomeni, da so na splo\u0161no priznani kot varni.<\/p>\n\n

Terpeni torej veljajo za spojine, katerim pripisujejo pozitivne u\u010dinke na na\u0161e zdravje. V kombinaciji s kanabinoidi se njihov u\u010dinek bistveno pove\u010da, govorimo o \u00bbentourage\u00ab efektu. Konoplja je torej rastlina, ki vsebuje velike koli\u010dine kanabinoidov, hkrati so v konoplji prisotni tudi terpeni, ki jih sicer najdemo v drugih rastlinah, na primer limonen v citrusih, pinen v borovcih, mircen in humulen v hmelju, linalol v sivki, kariofilen v popru, kariofilen oksid v arniki, nerolidol v pomaran\u010dah, fitol v zelenem \u010daju, itd.<\/p>\n\n

\"\"\n
Vir slike: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3165946\/<\/a><\/figcaption>\n<\/figure>\n\n

Povzeto iz:
https:\/\/www.projectcbd.org\/science\/terpenes-entourage-effect<\/a>
https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3165946\/<\/a><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\tNe spreglejte\t\t\t\t<\/p>\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tV trgovino<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\u017delim izvedeti ve\u010d<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Terpeni so hlapne aromati\u010dne molekule, mo\u010dnega vonja in okusa. Izkazalo se je, da so terpeni zdravi za ljudi in rastline. Zakaj pa delujejo sinergijsko v povezavi s kanabinoidi?<\/p>\n","protected":false},"author":2,"featured_media":7420,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[56,70],"tags":[65,57,81],"class_list":["post-7410","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-konoplja","category-terpeni","tag-kanabinoidi","tag-konoplja","tag-terpeni"],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/05\/Terpeni-Entourage-Hempethica-Widlab.png?fit=600%2C600&ssl=1","jetpack-related-posts":[{"id":6922,"url":"https:\/\/www.hempethica.com\/si\/konoplja-na-splosno\/","url_meta":{"origin":7410,"position":0},"title":"Na splo\u0161no o konoplji","author":"ekipa Hempethica","date":"09\/04\/2021","format":false,"excerpt":"Ena izmed zadnjih raziskav nem\u0161kih raziskovalcev, kakor tudi \u017ee ne\u0161teto raziskav raziskovalnih skupin po celem svetu, je pokazala, da konoplja in kanabinoidi krepijo imunski sistem. Terpeni, ki so prisotni v konoplji pa skrbijo za na\u0161e po\u010dutje.","rel":"","context":"In "Konoplja"","block_context":{"text":"Konoplja","link":"https:\/\/www.hempethica.com\/si\/konoplja\/"},"img":{"alt_text":"Konoplja","src":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/04\/Bud-001-e1623754182175.jpg?fit=600%2C600&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/04\/Bud-001-e1623754182175.jpg?fit=600%2C600&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/04\/Bud-001-e1623754182175.jpg?fit=600%2C600&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":6956,"url":"https:\/\/www.hempethica.com\/si\/terpeni-v-konoplji\/","url_meta":{"origin":7410,"position":1},"title":"Terpeni v konoplji","author":"ekipa Hempethica","date":"10\/04\/2021","format":false,"excerpt":"Kaj so terpeni? Zakaj so pomembni? Katere terpene poznamo? 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Ste tudi vi med njimi? Pomagate si lahko s kapljicami za bolj\u0161e po\u010dutje. 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