{"id":6925,"date":"2021-04-09T22:06:56","date_gmt":"2021-04-09T20:06:56","guid":{"rendered":"https:\/\/www.hempethica.com\/?p=6925"},"modified":"2021-12-23T13:25:41","modified_gmt":"2021-12-23T12:25:41","slug":"kanabinoidi-so-glavne-spojine-v-konoplji","status":"publish","type":"post","link":"https:\/\/www.hempethica.com\/si\/kanabinoidi-so-glavne-spojine-v-konoplji\/","title":{"rendered":"Kaj so kanabinoidi in kako delujejo?"},"content":{"rendered":"\t\t
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O kanabinoidih<\/h2>\n\n

Kanabinoidi so glavna skupina spojin, ki so prisotni v konoplji. So heterogena skupina spojin, katerih skupna zna\u010dilnost je, da se ve\u017eejo na kanabinoidne receptorje v telesu. V osnovi jih delimo na tri skupine glede na njihov izvor (endokanabinoidi, fitokanabinoidi in sinteti\u010dni kanabinoidi).<\/p>\n\n

Endokanabinoidi nastajajo v telesu, fitokanabinoidi nastajajo v rastlinah, sinteti\u010dne kanabinoide pa se sintezno pripravi v laboratoriju.<\/p>\n\n

Endokanabinoidi so \u010dloveku lastni kanabinoidi in jih na\u0161e telo proizvaja v \u017eiv\u010dnih celicah ter slu\u017eijo kot signalne molekule. Na\u0161e celice vsebujejo tudi kanabinoidne receptorje (CB1 in CB2), ki zaznavajo koli\u010dino oz. koncentracijo kanabinoidov v celicah. Tudi na\u0161i mo\u017egani zaznavajo spremembe v koncentraciji kanabinoidov v na\u0161em telesu ter se posledi\u010dno temu primerno tudi odzovejo.<\/p>\n\n

Fitokanabinoidi, kot \u017ee ime pove, so rastlinskega izvora in so po kemijski strukturi podobni endokanabinoidom in v na\u0161em telesu aktivirajo iste receprotorje (CB1 in CB2) kot endokanabinoidi. V svetu je poznanih \u017ee ve\u010d kot 140 kanabinoidov, med fitokanabinoidi sta tretnutno najbolj raziskana CBD in THC, zadnje raziskave pa vklju\u010dujejo tudi druge kanabinoide (CBN, CBC, CBG, itd).<\/p>\n\n

Sinteti\u010dne kanabinoide se s kemijsko sintezo pripravi v laboratoriju in so prisotni v veliki ve\u010dini farmacevtskih pripravkov. Raziskave so pokazale, da so v primerjavi z naravnimi oblikami kanabinoidov bistveno manj u\u010dinkoviti.<\/p>\n\n

Kanabinoide delimo v ve\u010d skupin, znotraj skupin pa najdemo ve\u010dje \u0161tevilo razli\u010dnih kanabinoidov.<\/p>\n\n

Ve\u010dina kanabinoidov nima psihoaktivnih u\u010dinkov, delujejo pozitivno na na\u0161e telo in imunski sistem. Kanabinoidi v kombinaciji s terpeni delujejo sinergijsko, s \u010dimer se njihov efekt pove\u010da (\u00bbentourage efekt\u00ab). Najbolj poznana in raziskana sta kanabinoida kanabinol (CBD), ki je psihoneaktiven kanabinoid in tetrahidrokanabinol (THC), ki je eden redkih kanabinoidov s psihoaktivnim efektom. Vedno ve\u010d raziskav je usmerjenih v raziskovanje sinergijskih u\u010dinkov kanabinoidov in terpenov.<\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"CBD\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Strukture glavnih kanabinoidov<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\"d8-THC-d8-tetrahidrokanabinol\"
d8-THC-d8-tetrahidrokanabinol<\/figcaption><\/figure><\/div>
\"d9-THC-d9-tetrahidrokanabinol\"
d9-THC-d9-tetrahidrokanabinol<\/figcaption><\/figure><\/div>
\"CBT-Kanabitriol\"
CBT-Kanabitriol<\/figcaption><\/figure><\/div>
\"CBL-Kanabiciklol\"
CBL-Kanabiciklol<\/figcaption><\/figure><\/div>
\"CBN-Kanabinol\"
CBN-Kanabinol<\/figcaption><\/figure><\/div>
\"CBE-Kanabielsoin\"
CBE-Kanabielsoin<\/figcaption><\/figure><\/div>
\"CBG-Kanabigerol\"
CBG-Kanabigerol<\/figcaption><\/figure><\/div>
\"CBDA-Kanabidiolna-kislina\"
CBDA-Kanabidiolna-kislina<\/figcaption><\/figure><\/div>
\"CBC-Kanabikromen\"
CBC-Kanabikromen<\/figcaption><\/figure><\/div>
\"CBD-Kanabidiol\"
CBD-Kanabidiol<\/figcaption><\/figure><\/div>\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t
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Kanabinoidi v naravi<\/h2>\n

<\/p>\n

Konoplja je edinstvena rastlina na zemlji, v kateri nastajajo kanabinoidi, najdemo pa jih tudi v nekaterih drugih rastlinah, za katere je znano da blagodejno vplivajo na ne\u0161e telo in po\u010dutje. Kanabinoide v manj\u0161ih koncentracijah najdemo v ameri\u0161kem slamniku, brazilski kre\u0161i, slamniku (strawflower) in nekaterih drugih.<\/p>\n

<\/p>\n

Ker nastajajo v rastlini, jim pravimo\u00a0fitokanabinoidi<\/strong><\/em>. V rastlinah so fitokanabinoidi predvsem v kislinski obliki. V na\u0161em telesu nastajajo endokanabinoidi in so v nekislinski obliki. Rastlinski fitokanabinoidi se s postopkom dekarboksilacije pretvorijo v nekislinske\/aktivne kanabinoide.<\/p>\n

<\/p>\n

V svetu najbolj poznan kanabinoid, CBD \u2013 kanabidiol, kakor tudi ostali kanabinodi, se v konoplji nahajajo v kislinski obliki (CBDA, THCA, CBGA, itd), v manj\u0161em dele\u017eu pa so prisotni kanabinodi tudi v nekislinski\/aktivni obliki (CBD, CBG, THC, itd).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Kako si lahko pomagamo?<\/h2>\n

V na\u0161em podjetju veliko \u010dasa namenimo raziskavam na podro\u010dju zdravilnih rastlin, predvsem konoplje in njenih ekstraktov. V kolikor pove\u017eemo prave rastline v pravo sinergijo, se lahko njihov efekt bistveno pove\u010da. Z na\u0161im lastnim znanjem smo razvili Konopljine CBD kapljice, ki imajo razli\u010den u\u010dinek delovanja glede na te\u017eave, s katerimi se vsakodnevno srere\u010dujemo. Na\u0161e izdelke nam pomagajo razvijati strokovnjaki iz razli\u010dnih podro\u010dij znotraj podjetja WidLab d.o.o.<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\tNe spreglejte\t\t\t\t<\/p>\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\"CBD\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\"Sleeper,\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tV trgovino<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tPreberi ve\u010d<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Kanabinoidi so glavna skupina spojin, ki so prisotni v konoplji. So heterogena skupina spojin, katerih skupna zna\u010dilnost je, da se ve\u017eejo na kanabinoidne receptorje v telesu. V osnovi jih delimo na tri skupine glede na njihov izvor (endokanabinoidi, fitokanabinoidi in sinteti\u010dni kanabinoidi).<\/p>\n","protected":false},"author":2,"featured_media":7433,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[56,69],"tags":[59,65,57],"class_list":["post-6925","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-konoplja","category-kanabinoidi","tag-cbd","tag-kanabinoidi","tag-konoplja"],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/04\/Kanabinoidi-Hempethica-widlab.png?fit=1500%2C1500&ssl=1","jetpack-related-posts":[{"id":10881,"url":"https:\/\/www.hempethica.com\/si\/pms-kanabinoidi-samopomoc-lajsanje-bolecin\/","url_meta":{"origin":6925,"position":0},"title":"PMS – predmenstrualni sindrom in pomo\u010d s konopljo","author":"ekipa Hempethica","date":"09\/06\/2022","format":false,"excerpt":"Predmenstrualni sindrom (PMS) je cikli\u010dni pojav nekaterih simptomov. Med zna\u010dilne PMS simptome spadajo bole\u010dine v hrbtu, napihnjenost, glavoboli, razdra\u017eljivost in splo\u0161na utrujenost. Ker kanabinoidi vplivajo na EKS z vzpostavljanjem ravnovesja in ker je koncentracija anandamida v maternici zelo visoka, lahko kanabinoidi tudi laj\u0161ajo simptome PMS.","rel":"","context":"In "Samozdravljenje"","block_context":{"text":"Samozdravljenje","link":"https:\/\/www.hempethica.com\/si\/samozdravljenje\/"},"img":{"alt_text":"PMS - Predmenstrualni sindrom in pomo\u010d s kanabinoidi","src":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2022\/06\/PMS-and-CBD.jpg?fit=600%2C600&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2022\/06\/PMS-and-CBD.jpg?fit=600%2C600&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2022\/06\/PMS-and-CBD.jpg?fit=600%2C600&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":7740,"url":"https:\/\/www.hempethica.com\/si\/endokanabinoidni-sistem-in-povezava\/","url_meta":{"origin":6925,"position":1},"title":"Endokanabinoidni sistem in uporaba kanabinoidov v medicini","author":"ekipa Hempethica","date":"13\/02\/2021","format":false,"excerpt":"Kaj je endokanabinoidni sistem (EKS)? Ali kanabinoide uporabljamo tudi v klasi\u010dni medicini? EKS je endogeni signalni mehanizem, ki je prisoten pri vseh vreten\u010darjih. Identificiranih je \u017ee preko 140 kanabinoidov in nekatere med njimi uporabljamo tudi v klasi\u010dni medicini za zdravljenje najte\u017ejih oblik kroni\u010dnih nevrodegenerativnih bolezni.","rel":"","context":"In "Kanabinoidi"","block_context":{"text":"Kanabinoidi","link":"https:\/\/www.hempethica.com\/si\/konoplja\/kanabinoidi\/"},"img":{"alt_text":"Endokanabinoidni sistem, ECS, kanabinoidi, CBD, Hempethica","src":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/07\/ECS-Hui-Chen-Lu-Hempethica.png?fit=600%2C600&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/07\/ECS-Hui-Chen-Lu-Hempethica.png?fit=600%2C600&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/07\/ECS-Hui-Chen-Lu-Hempethica.png?fit=600%2C600&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":7879,"url":"https:\/\/www.hempethica.com\/si\/svetovanje-glede-uporabe-kanabinoidov\/","url_meta":{"origin":6925,"position":2},"title":"Svetovanje glede uporabe konoplje in kanabinoidov","author":"ekipa Hempethica","date":"29\/07\/2021","format":false,"excerpt":"Konoplja in kanabinoidi? Komu je svetovanje namenjeno? Konoplja in njeni izvle\u010dki so v svetu vedno bolj priznani in postajajo del splo\u0161ne uporabe. Na strokovnem podro\u010dju uporabe kanabinoidov v zdravstvene namene prevladujejo Zdru\u017eene dr\u017eave Amerike, Kanada in Izrael. Konopljo in njene izvle\u010dke dandanes najdemo v razli\u010dnih oblikah. Znanstveno je ena najbolj\u2026","rel":"","context":"In "Samozdravljenje"","block_context":{"text":"Samozdravljenje","link":"https:\/\/www.hempethica.com\/si\/samozdravljenje\/"},"img":{"alt_text":"Svetovanje, Samozdravljenje, ICanna, CBD, kanabinoidi, cannabinoids, hempethica","src":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/07\/Svetovanje-kanabinoidi-CBD-Samozdravljenje-Hempethica.jpg?fit=600%2C600&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/07\/Svetovanje-kanabinoidi-CBD-Samozdravljenje-Hempethica.jpg?fit=600%2C600&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/07\/Svetovanje-kanabinoidi-CBD-Samozdravljenje-Hempethica.jpg?fit=600%2C600&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":7854,"url":"https:\/\/www.hempethica.com\/si\/imunski-sistem-in-kanabinoidi-povezava\/","url_meta":{"origin":6925,"position":3},"title":"Imunski sistem in kanabinoidi \u2013 kak\u0161na je povezava?","author":"ekipa Hempethica","date":"29\/07\/2021","format":false,"excerpt":"Kanabinoidi imajo sposobnost podpirati in\/ali zavirati imunski sistem, odvisno od mo\u017enosti in pogojev. V primerih, ko je na\u0161 imunski sistem oslabljen, potrebuje podporo. Obstajajo pa tudi primeri, ko je potrebno na\u0161 imunski sistem zavirati, kar je najbolj o\u010ditno pri avtoimunskih boleznih. Okvare imunskega sistema lahko vodijo v avtoimune bolezni, vnetja\u2026","rel":"","context":"In "Samozdravljenje"","block_context":{"text":"Samozdravljenje","link":"https:\/\/www.hempethica.com\/si\/samozdravljenje\/"},"img":{"alt_text":"Imunski sistem, Cannabinoids, Immune system, CBD, Cannabis, Hempethica","src":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/07\/Cannabis-Health-Immune-Hempethica.jpg?fit=600%2C600&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/07\/Cannabis-Health-Immune-Hempethica.jpg?fit=600%2C600&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/07\/Cannabis-Health-Immune-Hempethica.jpg?fit=600%2C600&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":6922,"url":"https:\/\/www.hempethica.com\/si\/konoplja-na-splosno\/","url_meta":{"origin":6925,"position":4},"title":"Na splo\u0161no o konoplji","author":"ekipa Hempethica","date":"09\/04\/2021","format":false,"excerpt":"Ena izmed zadnjih raziskav nem\u0161kih raziskovalcev, kakor tudi \u017ee ne\u0161teto raziskav raziskovalnih skupin po celem svetu, je pokazala, da konoplja in kanabinoidi krepijo imunski sistem. Terpeni, ki so prisotni v konoplji pa skrbijo za na\u0161e po\u010dutje.","rel":"","context":"In "Konoplja"","block_context":{"text":"Konoplja","link":"https:\/\/www.hempethica.com\/si\/konoplja\/"},"img":{"alt_text":"Konoplja","src":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/04\/Bud-001-e1623754182175.jpg?fit=600%2C600&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/04\/Bud-001-e1623754182175.jpg?fit=600%2C600&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/www.hempethica.com\/wp-content\/uploads\/2021\/04\/Bud-001-e1623754182175.jpg?fit=600%2C600&ssl=1&resize=525%2C300 1.5x"},"classes":[]},{"id":7516,"url":"https:\/\/www.hempethica.com\/si\/kronicne-bolecine-pomoc-s-kanabinoidi\/","url_meta":{"origin":6925,"position":5},"title":"Kako lahko kanabinoidi pomagajo izbolj\u0161ati kakovost \u017eivljenja bolnikom s kroni\u010dnimi bole\u010dinami?","author":"ekipa Hempethica","date":"23\/06\/2021","format":false,"excerpt":"Ste tudi vi tisti, ki se spopadajo z bole\u010dinami na dnevni ravni? Vas kroni\u010dne bole\u010dine utrujajo? Se sre\u010dujete s kroni\u010dno bole\u010dino, ki ostaja tudi po tem, ko osnovni vzrok bolezni ali po\u0161kodbe izgine? 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